Contemporary Issues in the Management of Patients With Primary Biliary Cholangitis: An Interprofessional Approach

To participate in this activity, please:

An interprofessional faculty of gastroenterology clinicians discuss real-world issues in managing patients with primary biliary cholangitis. Two mini-lectures serve as the foundation for understanding the diagnostic evaluation and risk factors of primary biliary cholangitis. Three cases foster a robust discussion, among the 5 faculty, of clinical decision-making around the roles, benefits, and limitations of approved and investigational pharmacologic treatment options. The program format fosters critical thinking and application of material to patient cases, allowing participants to benefit from the insights provided by the faculty.

The lectures are also available as a podcast: You may listen here

Course Credit:

1 AAPA Category I Hour
1 ACPE Contact Hour
1 AMA PRA Category 1 CreditTM
1 ANCC Contact Hour
1 CA-BRN Contact Hour
1 Pharmacology Hour


Opens: 2023-09-30
Closes: 2024-09-30

Target Audience:

This activity was developed for gastroenterologists, hepatologists, primary care physicians, nurse practitioners, physician assistants/associates, and pharmacists who have a role in the diagnosis, management, and monitoring of patients with primary biliary cholangitis (PBC).

This activity is supported by an educational grant from Intercept.


In support of improving patient care, Annenberg Center for Health Sciences at Eisenhower (Annenberg Center) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The Annenberg Center for Health Sciences at Eisenhower designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Annenberg Center for Health Sciences at Eisenhower designates this knowledge-based activity for a maximum of 1 hour . Credit will be provided to NABP CPE Monitor within 60 days after the activity completion.

The Annenberg Center has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1 hour AAPA Category 1 CME credits. Approval is valid until September 30, 2024. PAs should only claim credit commensurate with the extent of their participation.

Annenberg Center for Health Sciences at Eisenhower designates this enduring activity for a maximum of 1 ANCC contact hour, including 1 pharmacology hour.

Provider is approved by the California Board of Registered Nursing, Provider #13664, for 1 contact hour.
To receive credit for education contact hours outside of the state of California, please check with your state board of registered nursing for reciprocity.
This activity was planned by and for the healthcare team, and learners will receive 1 Interprofessional Continuing Education (IPCE) credit(s) for learning and change.

Additional Content Planners

Heather Jimenez, MSN, FNP-C (Nurse Planner)
No significant relationships to disclose.

Kam A. Newman, MD (Peer Reviewer)
No significant relationships to disclose.

Michael Smith, PharmD, BCPS (Medical Writer)

Consultant: Wolters-Kluwer

Annenberg Center for Health Sciences

Staff at the Annenberg Center for Health Sciences at Eisenhower have no relevant financial relationships to disclose.

All of the financial relationships listed for these individuals have been mitigated.

    Presenting Faculty

  • Shubha Bhat, PharmD, MS, BCACP

    Clinical Pharmacy Specialist - Gastroenterology
    Digestive Disease & Surgery Institute
    Cleveland Clinic
    Cleveland, Ohio

  • James Boyer, MD

    Ensign Professor of Medicine (Digestive Diseases)
    Yale University School of Medicine
    New Haven, Connecticut

  • Sarah Enslin, PA-C

    APP Manager, Medicine Service Line
    Lead APP, Gastroenterology and Hepatology
    University of Rochester Medical Center
    Rochester, New York

  • Donald Gardenier, DNP, FNP-C

    Nurse Practitioner, Gastroenterology

  • Seth N. Sclair, MD

    Associate Professor of Medicine
    Case Western Reserve University School of Medicine
    Division of Gastroenterology and Liver Disease
    Medical Director, Liver Transplant Program
    University Hospitals Cleveland Medical Center
    Digestive Health Institute
    Cleveland, Ohio

Learning Objectives

  • Identify appropriate tests and support decision-making in the diagnosis of primary biliary cholangitis (PBC)
  • Engage in best practices in the use of ursodiol as initial therapy for PBC, including monitoring response to therapy
  • Incorporate obeticholic acid into routine care for patients with PBC who do not respond to or are intolerant of ursodiol
  • Demonstrate an understanding of the importance and role of the interprofessional care team

Faculty Disclosures

Shubha Bhat, PharmD, MS, BCACP

Advisory Board: Boehringer Ingelheim, Bristol Myers Squibb, Pfizer, Pharmacosmos

Consultant: AbbVie

Speakers Bureau: Eli Lilly, Prometheus Laboratory

James Boyer, MD

No relationships to disclose.

Sarah Enslin, PA-C

Advisory Board: Castle Biosciences, Exact Sciences, Regeneron Pharmaceuticals

Donald Gardenier, DNP, FNP-C

No relationships to disclose.

Seth N. Sclair, MD

Speakers Bureau: Mallinckrodt