Annenberg Center for Health Sciences

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Fluticasone

A 2019 randomized, placebo-controlled phase 3 trial by Lucendo et al. on behalf of an international eosinophil disease study group to assess the effectiveness and tolerability of a topical budesonide orodispersible tablet in adults with active eosinophilic esophagitis reported which one of the following results?

At 6 weeks, more than half of patients treated with topical budesonide achieved complete histologic remission.
The histologic remission rate depended on the blood eosinophil count at baseline.
The histologic remission rate depended on which segment of the esophagus was affected.
Oral candidiasis occurred in 25% of patients treated with topical budesonide.

A: At 6 weeks, more than half of patients treated with topical budesonide achieved complete histologic remission.
B: The histologic remission rate depended on the blood eosinophil count at baseline.
C: The histologic remission rate depended on which segment of the esophagus was affected.
D: Oral candidiasis occurred in 25% of patients treated with topical budesonide.