Overview

Leslie Cho, MD, and Jennifer G. Robinson, MD, MPH, provide their perspectives on issues related to the evolving role and value of PCSK9 inhibitors in the management of patients with atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia. Drs. Cho and Robinson examine the impact of PCSK9 inhibitors on patients with elevated low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B, including the benefits and risks of lowering LDL-C below 25 mg/dL. They discuss the evidence regarding possible effects of PCSK9 inhibitors on cognition and antibody formation. Suggestions are offered for overcoming restrictions to PCSK9 inhibitor therapy implemented by payers.

Content Areas

  • Proprotein convertase subtilisin-kexin type 9 inhibitors
  • Low-density lipoprotein cholesterol hypercholesterolemia
  • Apolipoprotein B
  • Safety
  • Overcoming payer restrictions

Target Audience

This activity was developed for cardiologists, cardiology fellows, nurses, nurse practitioners, physician assistants, pharmacists and other health care professionals who have an interest in lipid management.


This activity is supported by educational funding provided by Amgen.

Faculty

Leslie Cho, MD
Leslie Cho, MD
Director, Women's Cardiovascular Center; Section Head
Preventive Cardiology and Rehabilitation, Cleveland Clinic
Cleveland, Ohio
Jennifer G. Robinson, MD, MPH
Jennifer G. Robinson, MD, MPH
Professor, Departments of Epidemiology, and Medicine (Division of Cardiology)
Director, Prevention Intervention Center
College of Public Health
University of Iowa
Iowa City, Iowa
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Cme credit

Available Credit: 0.50 AMA PRA Category 1 Credit™.
0.50 ACPE Contact Hour
0.50 AANP Contact Hour
0.50 ANCC Contact Hour
0.50 AAPA Category I Hour
Opens: October 01, 2017
Expires: September 30, 2018
Target Audience: Cardiologists
Fellows
Nurses
Nurse Practitioners
Physician Assistants
Pharmacists
Other Health Care Providers